\u809d\u764c\u306f\u4ee5\u524d\u306fC\u578b\u809d\u708e\u304b\u3089\u767a\u751f\u3059\u308b\u306e\u304c\u307b\u3068\u3093\u3069\u3067\u3042\u3063\u305f\u304c\u3001\u6700\u8fd1\u3067\u306f40%\u8fd1\u304f\u304c\u975eB\u975eC\u306b\u3088\u308b\u3082\u306e\u306b\u306a\u3063\u3066\u3044\u308b\u3002\u7cd6\u5c3f\u75c5\u60a3\u8005\u3055\u3093\u306e3\u4eba\u306b\u4e00\u4eba\u306f\u764c\u3067\u4ea1\u304f\u306a\u308a\u3001\u809d\u764c\u304c\u3082\u3063\u3068\u591a\u304f\u3001\u6b21\u3044\u3067\u81b5\u81d3\u764c\u3001\u5927\u8178\u764c\u3067\u3042\u308b\u3002<\/p>\n
C\u578b\u809d\u708e\u3067\u306f\u7a7a\u8179\u6642\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u5024\u304c\u9ad8\u304f\u3001\u3053\u308c\u306f\u4ed6\u306e\u809d\u75be\u60a3\u3088\u308a\u3082\u9ad8\u304f\u3001HCV\u30a6\u30a4\u30eb\u30b9\u304c\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u963b\u5bb3\u3059\u308b\u305f\u3081\u3067\u3042\u308b\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u9ad8\u3044\u3068\u809d\u764c\u306e\u767a\u751f\u304c\u9ad8\u304f\u306a\u308b\u3002\u809d\u786c\u5909\u60a3\u8005\u3067\u306f\u3001\u81b5\u81d3\u306e\u30e9\u30f3\u30b2\u30eb\u30cf\u30f3\u30b9\u5cf6\u304c\u5897\u5927\u3057\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5408\u6210\u5206\u6ccc\u3082\u591a\u304f\u306a\u3063\u3066\u3044\u308b\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u306b\u306f\u8840\u7cd6\u3092\u4e0b\u3052\u308b\u4f5c\u7528\u3068\u7d30\u80de\u5897\u6b96\u4f5c\u7528\u304c\u3042\u308a\u3001\u5897\u6b96\u30db\u30eb\u30e2\u30f3\u3068\u3057\u3066\u306e\u4f5c\u7528\u3092\u6301\u3063\u3066\u3044\u308b\u3002\u81b5\u81d3\u304b\u3089\u5206\u6ccc\u3055\u308c\u305f\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u9580\u8108\u304b\u3089\u809d\u81d3\u3092\u307e\u305a\u901a\u308b\u305f\u3081\u3001\u809d\u81d3\u306f\u9ad8\u6fc3\u5ea6\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u306b\u3055\u3089\u3055\u308c\u3066\u3044\u308b\u305f\u3081\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u304c\u591a\u3044\u3068\u809d\u81d3\u764c\u306b\u306a\u308a\u3084\u3059\u3044\u3002<\/p>\n
\u809d\u764c\u60a3\u8005\u3067\u306f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u5f37\u3044\u3068\u4e88\u5f8c\u304c\u60aa\u304f\u3001\u809d\u764c\u306e\u5206\u5316\u5ea6\u304c\u4f4e\u304f\u306a\u308b\u3002NASH\u304b\u3089\u767a\u751f\u3059\u308b\u809d\u764c\u3067\u306f\u3001\u6700\u521d\u304b\u3089\u4e2d\u5206\u5316\u3084\u4f4e\u5206\u5316\u306e\u764c\u304c\u767a\u751f\u3059\u308b\u3002C\u578b\u809d\u708e\u3067\u306f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u9ad8\u3044\u3068\u3001\u30a6\u30a4\u30eb\u30b9\u3092\u99c6\u9664\u3057\u305f\u5f8c\u306e\u809d\u764c\u306e\u767a\u751f\u304c\u9ad8\u304f\u306a\u308b\u3002<\/p>\n
\u7cd6\u5c3f\u75c5\u304c\u3042\u308b\u3068\u8102\u80aa\u809d\u304b\u3089\u306e\u809d\u764c\u767a\u751f\u983b\u5ea6\u304c\u9ad8\u304f\u306a\u308b\u3002NAFLD\u306e0.25%\u306b\u809d\u764c\u304c\u767a\u751f\u3059\u308b\u304c\u3001\u7cd6\u5c3f\u75c5\u5408\u4f75\u306e\u306a\u3044\u60a3\u8005\u3055\u3093\u304b\u3089\u306f\u809d\u764c\u306e\u767a\u751f\u304c\u306a\u304f\u3001\u7cd6\u5c3f\u75c5\u3092\u5408\u4f75\u3057\u3066\u3044\u308b\u3068\u6ce8\u610f\u304c\u5fc5\u8981\u3002<\/p>\n
\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u4ee5\u5916\u306e\u8102\u80aa\u809d\u3092NAFLD\u3068\u5206\u985e\u3055\u308c\u3001\u6700\u8fd1\u3067\u306f\u85ac\u5264\u8a98\u767a\u6027NAFLD\u304c\u554f\u984c\u3068\u306a\u3063\u3066\u3044\u308b\u3002\u8102\u80aa\u809d\u3092\u304d\u305f\u3059\u85ac\u5264\u3068\u3057\u3066\u306f\u3001\u30a2\u30df\u30aa\u30c0\u30ed\u30f3\u3001\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3\u3001MTX\u3001\u30ea\u30e5\u30fc\u30d7\u30ec\u30ea\u30f3\u3001\u30ab\u30eb\u30de\u30d0\u30bc\u30d4\u30f3\u3001\u30d0\u30eb\u30d7\u30ed\u9178\u306a\u3069\u3002<\/p>\n
PNPLA3\u306f\u552f\u4e00NAFLD\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u3067\u3042\u308a\u3001\u30ea\u30d1\u30fc\u30bc\u6d3b\u6027\u3092\u4fc3\u9032\u3055\u305b\u3066\u3001\u8102\u80aa\u3092\u5206\u89e3\u3059\u308b\u86cb\u767d\u3092\u30b3\u30fc\u30c9\u3059\u308b\u907a\u4f1d\u5b50\u3067\u3042\u308b\u3002\u80a5\u6e80\u3082\u306a\u3044\u65b9\u3067\u9ad8\u5ea6\u306e\u8102\u80aa\u809d\u304c\u3042\u308b\u5834\u5408\u306b\u307f\u3089\u308c\u308b\u304c\u3001\u73fe\u5728\u3067\u306f\u6e2c\u5b9a\u3067\u304d\u306a\u3044\u305f\u3081\u8a3a\u65ad\u3067\u304d\u306a\u3044\u3002<\/p>\n
NAFLD\u306e\u81ea\u7136\u7d4c\u904e\u306f\u30014-8%\/y\u304cNASH\u306b\u79fb\u884c\u3057\u3001\u305d\u306e0.8-1.6%\/y\u304cNASH\u809d\u786c\u5909\u306b\u9032\u5c55\u3057\u3001\u305d\u306e0.1-0.2%\/y\u306b\u809d\u764c\u304c\u767a\u751f\u3059\u308b\u3002HCV\u3088\u308a\u764c\u306e\u767a\u751f\u983b\u5ea6\u306f\u5c11\u306a\u3044\u304c\u3001\u30d9\u30fc\u30b9\u306eNAFLD\u306e\u60a3\u8005\u6570\u304c\u975e\u5e38\u306b\u591a\u3044\u305f\u3081\u3001\u809d\u764c\u306e\u767a\u751f\u6570\u3082\u591a\u304f\u306a\u308b\u3002<\/p>\n
NASH\u306b\u306a\u3063\u3066\u3044\u308b\u304b\u3069\u3046\u304b\u306f\u3001\u6700\u8fd1\u3067\u306f\u751f\u691c\u3092\u3057\u306a\u3044\u975e\u4fb5\u8972\u7684\u306a\u8a55\u4fa1\u3067\u5224\u5b9a\u3059\u308b\u3002<\/p>\n
Fib-4\u3000Index\u3000\u3000\uff08\u5e74\u9f62\uff58AST\uff09\/\uff08\u8840\u5c0f\u677f\uff58\uff08ALT)1\/2\uff09<\/p>\n
Fib4\u304c2\u3092\u8d85\u3048\u308b\u3068NASH\u306e\u53ef\u80fd\u6027\u3042\u308a\u3002<\/p>\n
\u8840\u6db2\u691c\u67fb\u3067\u809d\u7dda\u7dad\u5316\u306e\u7a0b\u5ea6\u3092\u8868\u3059M2BPGi\u304c1\u3092\u8d85\u3048\u308b\u3068\u7dda\u7dad\u5316\u304c\u3042\u308b\u3068\u5224\u65ad<\/p>\n
Fibroscan\u3067\u809d\u81d3\u306e\u9ad8\u5ea6\u3092\u6e2c\u5b9a\u3059\u308b<\/p>\n
\u3053\u306e3\u3064\u306e\u65b9\u6cd5\u30671\u3064\u3067\u3082\u967d\u6027\u3067\u3042\u308c\u3070\u3001\u809d\u764c\u306e\u767a\u751f\u983b\u5ea6\u304c\u9ad8\u304f\u306a\u308b\u305f\u3081\u901a\u5e38\u306eC\u578b\u809d\u708e\u306b\u6e96\u3058\u305f\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002<\/p>\n
\u8102\u80aa\u809d\u3067\u306e\u809d\u81d3\u306e\u786c\u3055\u304c\u786c\u304f\u306a\u308b\u3068\u4e88\u5f8c\u4e0d\u826f\u3068\u306a\u308b\u3001HbA1\uff43\uff1c6.3\u3067\u3042\u308c\u3070\u809d\u7dda\u7dad\u5316\u306f\u307b\u3068\u3093\u3069\u306a\u3044\u3002<\/p>\n
\u6709\u9178\u7d20\u904b\u52d5\u3068\u30ec\u30b8\u30b9\u30bf\u30f3\u30b9\u904b\u5ea6\u3067\u306f\u3069\u3061\u3089\u3082\u8102\u80aa\u809d\u306b\u52b9\u679c\u304c\u3042\u308b\u3002\u6709\u9178\u7d20\u904b\u52d5\u306f\u307d\u3063\u3061\u3083\u308a\u3057\u305f\u7537\u6027\u3067\u52b9\u679c\u304c\u3042\u308b\u3002\u3067\u304d\u308c\u30701\u56de40\u5206\u3001\u90313\u56de\u5b9f\u65bd\u3059\u308b\u3068\u52b9\u679c\u304c\u3042\u308b\u3002\u4f53\u91cd\u6e1b\u5c11\u304c\u306a\u304f\u3066\u3082\u904b\u52d5\u3092\u3059\u308b\u3068\u8102\u80aa\u809d\u306f\u6539\u5584\u3059\u308b\u3002\u7b4b\u8089\u91cf\u304c\u5897\u3048\u306a\u304f\u3066\u3082\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306f\u6539\u5584\u3059\u308b\u3002\u904b\u52d5\u3059\u308b\u3068\u7b4b\u8089\u3067\u30de\u30a4\u30aa\u30ab\u30a4\u30f3\u3068\u547c\u3070\u308c\u308b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u304c\u7523\u751f\u3055\u308c\u3001\u6e56\u306e\u5909\u5316\u304c\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3002\u30ec\u30b8\u30b9\u30bf\u30f3\u30b9\u904b\u52d5\u306e\u65b9\u304c\u3001\u30de\u30a4\u30aa\u30ab\u30a4\u30f3\u304c\u591a\u304f\u7523\u751f\u3055\u308c\u308b\u305f\u3081\u3001\u307e\u305a\u30ec\u30b8\u30b9\u30bf\u30f3\u30b9\u904b\u52d5\u3092\u3057\u3066\u304b\u3089\u3001\u6709\u9178\u7d20\u904b\u52d5\u3092\u3059\u308b\u3068\u52b9\u679c\u7684\u3067\u3042\u308b\u3002<\/p>\n
\u5206\u679d\u9396\u30a2\u30df\u30ce\u9178BCAA\u306f\u3001\u30ed\u30a4\u30b7\u30f3\u304c\u7b4b\u8089\u7d30\u80de\u3092\u5897\u6b96\u3055\u305b\u308b\u4f5c\u7528\u304c\u3042\u308a\u3001\u904b\u52d5\u5f8c\u306e\u7b4b\u8089\u75db\u304c\u8d77\u3053\u308a\u306b\u304f\u3044\u3002BCAA\u306f\u767a\u304c\u3093\u6291\u5236\u52b9\u679c\u304c\u3042\u308b\u3002BCAA\u306f\u7b4b\u8089\u5185\u3067\u4f5c\u7528\u3057\u3001\u80a5\u6e80\u3084\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306b\u95a2\u4e0e\u3059\u308b\u809d\u764c\u306e\u767a\u751f\u3092\u6291\u5236\u3059\u308b\u3002\u30ab\u30eb\u30cb\u30c1\u30f3\u3084\u4e9c\u925b\u306f\u809d\u81d3\u5185\u3067\u30a2\u30f3\u30e2\u30cb\u30a2\u7523\u751f\u3092\u6291\u5236\u3059\u308b\u3002<\/p>\n
\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4f5c\u7528\u306e\u3042\u308bSU\u5264\u306f\u809d\u764c\u306e\u767a\u751f\u3092\u8a98\u767a\u3059\u308b\u3002\u30e1\u30c8\u30db\u30eb\u30df\u30f3\u306f\u809d\u764c\u3092\u6291\u5236\u3057\u3001\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\u306f\u3001BMI24\u4ee5\u4e0a\u306e\u4eba\u3067\u809d\u764c\u306e\u767a\u751f\u3092\u6291\u5236\u3059\u308b\u3002<\/p>\n
\u809d\u7d30\u80de\u764c\u3067\u306fDPP4\u306e\u767a\u73fe\u304c\u4ea2\u9032\u3057\u3066\u304a\u308a\u3001\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u306eDPP4\u963b\u5bb3\u85ac\u304c\u6a5f\u5e8f\u306f\u4e0d\u660e\u3067\u3042\u308b\u304c\u3001\u809d\u764c\u306e\u767a\u751f\u3092\u6291\u5236\u3059\u308b\u3002<\/p>\n
\u81b5\u81d3\u764c\u3067\u306f\u3001SGLT-2\u304c\u9ad8\u767a\u73fe\u3057\u3066\u304a\u308a\u3001\u304c\u3093\u7d30\u80de\u306e\u7cd6\u306e\u53d6\u8fbc\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001SGLT2\u963b\u5bb3\u85ac\u306b\u3066\u81b5\u81d3\u764c\u3067\u306e\u7cd6\u306e\u53d6\u8fbc\u3092\u6291\u5236\u3057\u3066\u764c\u3092\u6b7b\u6ec5\u3055\u305b\u308b\u3002<\/p>\n
<\/p>\n
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