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\u514d\u75ab\u72b6\u614b\u306b\u304a\u3051\u308b\u809d\u708e\u30a6\u30a4\u30eb\u30b9\u5bfe\u7b56<\/p>\n
\u514d\u75ab\u6291\u5236\u72b6\u614b\u306b\u3088\u308a\u3001\u30a6\u30a4\u30eb\u30b9\u306f\u5897\u6b96\u3001\u809d\u708e\u306f\u6291\u5236\u3055\u308c\u308b\u305f\u3081\u3053\u306e\u30d0\u30e9\u30f3\u30b9\u3067\u75c5\u614b\u304c\u6c7a\u307e\u308b\u3002\u69d8\u3005\u306a\u514d\u75ab\u6291\u5236\u5264\u306b\u6ce8\u610f\u66f8\u304d\u304c\u3042\u308b\u304c\u3001\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u3001\u30d5\u30e9\u30bf\u30e9\u30d3\u30f3\u306e3\u3064\u304c\u660e\u3089\u304b\u306bHBV\u518d\u6d3b\u6027\u5316\u3092\u8d77\u3053\u3057\u3084\u3059\u3044\u3002<\/p>\n
\u30dd\u30a4\u30f3\u30c8\u2460\u3000\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3067HBc\u6297\u4f53\u3092\u6e2c\u5b9a\u3059\u308b\u3002HCV\u6297\u4f53\u967d\u6027\u3067\u3042\u308c\u3070\u3001HCV-RNA\u3092\u6e2c\u5b9a\u3057\u9670\u6027\u3067\u3042\u308c\u3070\u65e2\u611f\u67d3\u3002HBV\u3067\u306f\u3001HBs\u6297\u539f\u3001HBc\u6297\u4f53\u3001HBs\u6297\u4f53\u3069\u308c\u304b\u304c\u967d\u6027\u3067\u3042\u308c\u3070\u3001\u30ad\u30e3\u30ea\u30a2\u304b\u65e2\u611f\u67d3\u3067\u3042\u308a\u3001HBV-DNA\uff08\u30ea\u30eb\u30bf\u30a4\u30e0PCR\uff09\u3092\u6e2c\u5b9a\u3059\u308b\u3002<\/p>\n
\u30dd\u30a4\u30f3\u30c8\u2461\u3000C\u578b\u809d\u708e\u306f\u5358\u7d14\u3067\u3042\u308a\u6839\u6cbb\u53ef\u80fd\u3002\u809d\u7dda\u7dad\u5316\u304c\u4e00\u5b9a\u901f\u5ea6\u3067\u6162\u6027\u809d\u708e\u3001\u809d\u786c\u5909\u3001\u809d\u7d30\u80de\u764c\u3068\u9032\u307f\u3001\u7dda\u7dad\u5316\u306e\u7a0b\u5ea6\u304c\u8840\u5c0f\u677f\u6570\u3067\u63a8\u6e2c\u3067\u304d\u308b\u305f\u3081\u764c\u306e\u767a\u751f\u7387\u3082\u63a8\u6e2c\u3067\u304d\u308b\u3002HCV\u611f\u67d3\u8005\u306e\u7d0430%\u306f\u30a6\u30a4\u30eb\u30b9\u304c\u5b8c\u5168\u306b\u6392\u9664\u3055\u308c\u6cbb\u7652\u306b\u3044\u305f\u308b\u3002HCV\u6297\u4f53\u967d\u6027\u3001HCV-RNA\u9670\u6027\u3067\u3042\u308c\u3070\u6cbb\u7652\u3068\u5224\u65ad\u3057\u653e\u7f6e\u53ef\u3002\u57fa\u672c\u7684\u306bRNA\u30a6\u30a4\u30eb\u30b9\u306f\u6839\u6cbb\u3067\u304d\u308b\u304c\u3001DNA\u30a6\u30a4\u30eb\u30b9\uff08HBV\u3001CMV\u3001EBV\u3001HSV\u3001HPV\uff09\u306f\u6839\u6cbb\u3067\u304d\u305a\u3001\u751f\u6daf\u6f5c\u4f0f\u611f\u67d3\u306b\u306a\u308b\u3002C\u578b\u809d\u708e\u306f\u3001DAA\u306e\u767b\u5834\u306b\u3088\u308a\uff0c\u6839\u6cbb\u53ef\u80fd\u3068\u306a\u3063\u305f\u3002SVR24\u304c\u9054\u6210\u3067\u304d\u308c\u3070\u6839\u6cbb\u3057\u305f\u3068\u5224\u65ad\u3002<\/p>\n
\u30dd\u30a4\u30f3\u30c8\u2462\u3000C\u578b\u809d\u708e\u306f\u514d\u75ab\u6291\u5236\u72b6\u614b\u3068\u306a\u3063\u3066\u3082\u307b\u3068\u3093\u3069\u4f55\u3082\u8d77\u3053\u3089\u306a\u3044\u3002HCV\u967d\u6027\u4f8b\u306bRA\u6cbb\u7642\u306a\u3069\u306e\u514d\u75ab\u6291\u5236\u6cbb\u7642\u3092\u3057\u3066\u3082\u60aa\u5316\u306f\u307b\u3068\u3093\u3069\u306a\u304f\u3001MTX\u9577\u671f\u4f7f\u7528\u3057\u3066\u3082\u809d\u786c\u5909\u3078\u306e\u9032\u5c55\u306f\u3080\u3057\u308d\u5c11\u306a\u304f\u306a\u308b\u3002\u814e\u79fb\u690d\u3067\u3082\u4e88\u5f8c\u306b\u5909\u5316\u306a\u3057\u3002HCV\u967d\u6027\u3067\u3082\u3001\u514d\u75ab\u6291\u5236\u5264\u306e\u6e1b\u91cf\u306f\u4e0d\u8981\u3067\u3042\u308b\u3002<\/p>\n
\u30dd\u30a4\u30f3\u30c8\u2463\u3000HCV\u967d\u6027\u4f8b\u306f\u3001DAA\u6cbb\u7642\u306b\u3088\u308a2\u5264\u8010\u6027\u30a6\u30a4\u30eb\u30b9\u304c\u3067\u3066\u304a\u308a\u3001\u4f75\u7528\u7981\u5fcc\u85ac\uff08\u30a2\u30df\u30aa\u30c0\u30ed\u30f3\u3001Ca\u62ee\u6297\u85ac\u306a\u3069\uff09\u3082\u591a\u3044\u305f\u3081\u5c02\u9580\u533b\u3092\u7d39\u4ecb\u3059\u308b\u3053\u3068\u3092\u52e7\u3081\u308b<\/p>\n
\u30dd\u30a4\u30f3\u30c8\u2464\u3000B\u578b\u809d\u708e\u306f\u8907\u96d1\u3067\u6839\u6cbb\u3067\u304d\u306a\u3044\u3002\u4e00\u904e\u6027\u611f\u67d3\u306f\u7d0490%\u3067\u6cbb\u7652\u3059\u308b\u30021\u301c2\uff05\u6b7b\u4ea1\u30025\u624d\u672a\u6e80\u306b\u611f\u67d3\u3059\u308b\u3068\u6301\u7d9a\u611f\u67d3\u3068\u306a\u308a\u3001\u307b\u3068\u3093\u3069\u304c\u975e\u6d3b\u52d5\u6027\u30ad\u30e3\u30ea\u30a2\u3068\u306a\u308b\u3002\u4e00\u90e8\u306f\u6162\u6027\u809d\u708e\u3001\u809d\u786c\u5909\u3001\u809d\u7d30\u80de\u764c\u3068\u306a\u308b\u304c\u3001\u3069\u306e\u6bb5\u968e\u304b\u3089\u3067\u3082\u6025\u901f\u306b\u809d\u786c\u5909\u306b\u306a\u3063\u305f\u308a\u3001\u809d\u7d30\u80de\u764c\u304c\u767a\u751f\u3059\u308b\u3002\u6700\u8fd1\u306f\u30b8\u30a7\u30ce\u30bf\u30a4\u30d7A\u306b\u3088\u308a\u3001\u6210\u4eba\u611f\u67d3\u3067\u308210\uff05\u7a0b\u5ea6\u6162\u6027\u5316\u3059\u308b\u3002HBs\u6297\u539f\u3001HBc\u6297\u4f53\u3001HBs\u6297\u4f53\u306e\u6709\u7121\u306b\u3088\u308a\u672a\u611f\u67d3\u3001\u65e2\u611f\u67d3\u3001\u6301\u7d9a\u611f\u67d3\u306e3\u3064\u306b\u5206\u3051\u3089\u308c\u308b\u3002HBV\u306f\u30a6\u30a4\u30eb\u30b9\u91cf\u3068\u75c5\u52e2\u304c\u76f8\u95a2\u3057\u3001HBV-DNA 4.0\u672a\u6e80\u3067\u3042\u308c\u3070\u809d\u708e\u304c\u767a\u75c7\u3059\u308b\u3053\u3068\u306f\u306a\u304f\u3001\u809d\u9175\u7d20\u304c\u4e0a\u6607\u3057\u3066\u3044\u3066\u3082HBV-DNA\uff1c4.0\u3067\u3042\u308c\u3070\u3001HBV\u4ee5\u5916\u306e\u539f\u56e0\u3092\u8003\u3048\u308b\u3002<\/p>\n
\u30dd\u30a4\u30f3\u30c8\u2465\u3000HBV\u30ad\u30e3\u30ea\u30a2\u306e\u514d\u75ab\u6291\u5236\u72b6\u614b\u3067\u306f\u30a8\u30f3\u30c6\u30ab\u30d3\u30eb\u306e\u4e88\u9632\u6295\u4e0e\u3092\u5b9f\u65bd\u3059\u308b\u300220\u301c50%\u304c\u6d3b\u6027\u5316\u3057\u3001\u518d\u6d3b\u6027\u5316\u306e\u6b7b\u4ea1\u7387\u304c\u6025\u6027\u809d\u708e\u306e\u6b7b\u4ea1\u7387\u3088\u308a\u3082\u9ad8\u3044\u305f\u3081\u3001\u4e88\u9632\u6295\u4e0e\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002\u514d\u75ab\u6291\u5236\u6cbb\u7642\u3092\u958b\u59cb\u3057\u3001\u5f90\u3005\u306bHBV\u304c\u5897\u52a0\u3057\u3001\u6cbb\u7642\u4e2d\u6b62\u306b\u3088\u308b\u514d\u75ab\u56de\u5fa9\u6642\u306b\u809d\u708e\u304c\u767a\u75c7\u3059\u308b\u3002\u30a6\u30a4\u30b9\u30eb\u304c\u5897\u52a0\u3057\u3001\u809d\u708e\u304c\u767a\u75c7\u3059\u308b\u306e\u306b\u6700\u77ed\u3067\u308212\u9031\u306e\u4f59\u88d5\u304c\u3042\u308b\u305f\u3081\u3001HBV-DNA\u30921\u301c3\u30f6\u6708\u6bce\u306b\u30d5\u30a9\u30ed\u30fc\u3057\u30012.1\u3068\u306a\u308c\u3070\u30a8\u30f3\u30c6\u30ab\u30d3\u30eb\u306e\u4e88\u9632\u6295\u4e0e\u3092\u958b\u59cb\u3059\u308c\u3070\u9593\u306b\u5408\u3046\u3002\u614c\u3066\u3066\u514d\u75ab\u6291\u5236\u5264\u3092\u4e2d\u6b62\u3057\u306a\u3044\u3088\u3046\u306b\u3001\u4e2d\u6b62\u3059\u308b\u3068\u6025\u901f\u306b\u809d\u708e\u304c\u767a\u75c7\u3059\u308b\u3002<\/p>\n
\u30dd\u30a4\u30f3\u30c8\u2466\u3000HBV\u65e2\u611f\u67d3\u306f\u809d\u5185\u30a6\u30a4\u30b9\u30eb\u6f5c\u4f0f\u72b6\u614b\u3067\u3042\u308b\u3002\u809d\u79fb\u690d\u6642\u306b\u521d\u3081\u3066\u78ba\u8a8d\u3055\u308c\u305f\u3002HBc\u6297\u4f53\u967d\u6027\u306e\u30c9\u30ca\u30fc\u304b\u3089\u809d\u79fb\u690d\u3092\u884c\u3046\u3068\u3001\u30ec\u30b7\u30d4\u30a8\u30f3\u30c8\u306f100%B\u578b\u809d\u708e\u767a\u75c7\u3057\u305f\u3002\u305d\u308c\u307e\u3067\u306f\u3001\u8853\u524d\u306eHBs\u6297\u539f\u9670\u6027\u3092\u78ba\u8a8d\u3057\u3066\u304a\u308a\u3001\u8853\u8005\u3084\u8f38\u8840\u304b\u3089\u306e\u611f\u67d3\u3082\u7591\u308f\u308c\u305f\u304c\u3001HBc\u6297\u4f53\u967d\u6027\u8005\u306e\u809d\u7d30\u80de\u5185\u306b\u306f\u30a6\u30a4\u30b9\u30eb\u304c\u6b8b\u3063\u3066\u304a\u308a\u3001\u8907\u88fd\u3082\u3057\u3066\u3044\u308b\u3002\u81ea\u5df1\u306e\u514d\u75ab\u306b\u3088\u308a\u3001\u30a6\u30a4\u30b9\u30eb\u3092\u62bc\u3055\u3048\u8fbc\u3093\u3067\u3044\u308b\u304c\u3001\u30ec\u30b7\u30d4\u30a8\u30f3\u30c8\u306fHBV\u306b\u5bfe\u3059\u308b\u514d\u75ab\u3092\u3082\u3063\u3066\u3044\u306a\u3044\u305f\u3081100%\u767a\u75c7\u3059\u308b\u3002<\/p>\n
\u30dd\u30a4\u30f3\u30c8\u2467\u3000HBV\u65e2\u611f\u67d3\u3067\u306f\u3001HBV-DNA\u3092\u5b9a\u671f\u7684\u306b\u30d5\u30a9\u30ed\u30fc\u3059\u308b\u3002\u30a6\u30a4\u30eb\u30b9\u306e\u518d\u6d3b\u6027\u5316\u306f2\u301c5%\u7a0b\u5ea6\u3001\u514d\u75ab\u6291\u5236\u6cbb\u7642\u958b\u59cb\u3059\u308b\u3068\u3001\u307e\u305aHBV-DNA\u304c\u967d\u6027\u3068\u306a\u308a\u3001\u305d\u306e\u5f8cHBs\u6297\u539f\u967d\u6027\u3068\u306a\u308b\u3002\u809d\u708e\u767a\u75c7\u307e\u3067\u306b\u306f\u6700\u77ed\u3067\u308212\u9031\u9593\u306e\u4f59\u88d5\u304c\u3042\u308a\u3001\u30d5\u30a9\u30ed\u30fc\u306e\u671f\u9593\u3068\u3057\u3066\u306f1\u301c3\u30f6\u6708\u3068\u306a\u3063\u3066\u3044\u308b\u3002\u514d\u75ab\u6cbb\u7642\u958b\u59cb\u5f8c\u307b\u3068\u3093\u3069\u304c6\u30f6\u6708\u4ee5\u5185\u306b\u518d\u6d3b\u6027\u5316\u304c\u304a\u3053\u3063\u3066\u3044\u308b\u305f\u3081\u3001\u6cbb\u7642\u958b\u59cb6\u30f6\u6708\u4ee5\u5185\u306f1\u30f6\u6708\u6bce\u306b\u30016\u30f6\u6708\u4ee5\u964d\u306f3\u30f6\u6708\u6bce\u306b\u30d5\u30a9\u30ed\u30fc\u3059\u308b\u306e\u304c\u3088\u3044\u3002HBV-DNA2.1\u672a\u6e80\u3067\u3042\u308c\u30701\u30f6\u6708\u5f8c\u306b\u518d\u691c\u30012.1\u3068\u306a\u308c\u3070\u30a8\u30f3\u30c6\u30ab\u30d3\u30eb\u4e88\u9632\u6295\u4e0e\u958b\u59cb\u30014.0\u4ee5\u4e0a\u3068\u306a\u308c\u3070\u3059\u3050\u306b\u5c02\u9580\u533b\u7d39\u4ecb\u3002\u30a8\u30f3\u30c6\u30ab\u30d3\u30eb\u306e\u4e88\u9632\u6295\u4e0e\u306f\u3001\u4e00\u5ea6\u3067\u3082HBV-DNA\u304c\u967d\u6027\u3068\u306a\u3063\u3066\u3044\u308c\u3070\u4fdd\u5065\u9069\u5fdc\u3068\u306a\u308b\u3002<\/p>\n
\u30b9\u30c6\u30ed\u30a4\u30c9\u306f\u30010.5mg\/kg\u30922\u9031\u9593\u4ee5\u4e0a\u7d99\u7d9a\u3059\u308b\u5834\u5408\u306f\u514d\u75ab\u6291\u5236\u6cbb\u7642\u3068\u8003\u3048\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u304c\u5fc5\u8981<\/p>\n
<\/p>\n
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